Jalview is a free program for multiple sequence alignment editing, visualisation and analysis. It allows viewing and editing of sequence alignments, their analysis with phylogenetic trees and Principal Components Analysis (PCA) plots and exploration of molecular structures and annotation. Jalview also allows integration of variant data from genome sequencing together with interactive analysis of DNA, RNA and protein sequences, phylogenetics and three-dimensional structures of macromolecules.
The IUPHAR/BPS Guide to PHARMACOLOGY is an expert-curated resource of ligand-activity-target relationships, the majority of which come from high-quality pharmacological and medicinal chemistry literature. It is a freely available, searchable database of pharmacological information that includes quantitative data on drug targets and the prescription medicines and experimental drugs that act on them.
The HUGO Gene Nomenclature Committee is the only worldwide authority that assigns standardised nomenclature to human genes.
The GWAS Central resource provides a toolkit for integrative access and visualisation of summary-level genome-wide association study data gathered from various public sources and submitted by GWAS authors, while ensuring safe open access to prevent research participant identification.
Ensembl is a genome browser for vertebrate genomes that supports research in comparative genomics, evolution, sequence variation and transcriptional regulation.
DRSASP's flagship services are the JPred4 webserver for protein secondary structure and solvent accessibility prediction and the JABAWS 2.2 webserver for multiple sequence alignment, disorder prediction, amino acid conservation calculations, and specificity‐determining site prediction. DRSASP resources are available through conventional web interfaces and APIs but are also integrated into the Jalview sequence analysis workbench, which enables the composition of multitool interactive workflows.
CATH is a classification of protein structures downloaded from the Protein Data Bank. We group protein domains into superfamilies when there is sufficient evidence they have diverged from a common ancestor.
This service is run by Herriot-Watt University
The SEEK platform is a web-based resource for sharing heterogeneous scientific research datasets, models or simulations, processes and research outcomes. It preserves associations between them, along with information about the people and organisations involved.
InterMine is a software system that you can install on your own servers to make data available on the web. It integrates biological data sources, making it easy to query…